FEBS Letters
Volume 579, Issue 8 , Pages 1815-1820, 21 March 2005

Pathway information for systems biology

Edited by Robert Russell and Giulio Superti-Furga

Computational Biology Center, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Box 460, New York, NY 10021, USA

Accepted 1 February 2005. published online 09 February 2005.

Abstract 

Pathway information is vital for successful quantitative modeling of biological systems. The almost 170 online pathway databases vary widely in coverage and representation of biological processes, making their use extremely difficult. Future pathway information systems for querying, visualization and analysis must support standard exchange formats to successfully integrate data on a large scale. Such integrated systems will greatly facilitate the constructive cycle of computational model building and experimental verification that lies at the heart of systems biology.

Keywords: Pathway data integration, Pathway database, Standard exchange format, Ontology, Information system

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PII: S0014-5793(05)00170-5

doi:10.1016/j.febslet.2005.02.005

FEBS Letters
Volume 579, Issue 8 , Pages 1815-1820, 21 March 2005

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