Re-analysis of data and its integration

Abstract 

To understand a biological process it is clear that a single approach will not be sufficient, just like a single measurement on a protein – such as its expression level – does not describe protein function. Using reference sets of proteins as benchmarks different approaches can be scaled and integrated. Here, we demonstrate the power of data re-analysis and integration by applying it in a case study to data from deletion phenotype screens and mRNA expression profiling.

Keywords: Benchmarking, Data integration, Network analysis, Gene expression, Deletion phenotype