FEBS Letters
Volume 581, Issue 11 , Pages 2083-2088, 22 May 2007

Conformational changes of coat proteins during vesicle formation

Edited by Thomas Söllner

Biochemie Zentrum der Universität Heidelberg, Im Neuenheimer Feld 328, 3. OG, # 309, 69120 Heidelberg, Germany

Received 12 February 2007; received in revised form 26 February 2007; accepted 8 March 2007. published online 15 March 2007.

Abstract 

In coated vesicle formation, coat protein recruitment needs to be spatially and temporally controlled. The coating process involves conformational changes of the coat protein complexes that activate them for interaction with cargo or machinery components and coat polymerization. Here we discuss mechanisms that have emerged recently from studies of the clathrin adaptor and the COPI systems.

Keywords: Conformational changes, Vesicle formation

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PII: S0014-5793(07)00274-8

doi:10.1016/j.febslet.2007.03.020

FEBS Letters
Volume 581, Issue 11 , Pages 2083-2088, 22 May 2007

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