FEBS Letters
Volume 583, Issue 24 , Pages 3900-3904, 17 December 2009

Metabolic systems biology

Edited by Stefan Hohmann

Department of Bioengineering, UCSD, La Jolla, CA 92093-0412, United States

Received 8 July 2009; received in revised form 5 September 2009; accepted 15 September 2009. published online 22 September 2009.

Abstract 

The first full genome sequences were established in the mid-1990s. Shortly thereafter, genome-scale metabolic network reconstructions appeared. Since that time, we have witnessed an exponential growth in their number and uses. Here I discuss, from a personal point of view, four topics: (1) the placement of metabolic systems biology in the context of broader scientific developments, (2) its foundational concepts, (3) some of its current uses, and (4) some of the expected future developments in the field.

Keywords: Systems biology, Metabolism

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PII: S0014-5793(09)00719-4

doi:10.1016/j.febslet.2009.09.031

FEBS Letters
Volume 583, Issue 24 , Pages 3900-3904, 17 December 2009

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