FEBS Letters
Volume 583, Issue 23 , Pages 3746-3751, 3 December 2009

The yeast Golgi apparatus: Insights and mysteries

Edited by Antonella De Matteis

The University of Chicago, Molecular Genetics and Cell Biology, 920 East 58th St., Chicago, IL 60637, United States

Received 12 October 2009; received in revised form 26 October 2009; accepted 27 October 2009. published online 29 October 2009.

Abstract 

The Golgi apparatus is known to modify and sort newly synthesized secretory proteins. However, fundamental mysteries remain about the structure, operation, and dynamics of this organelle. Important insights have emerged from studying the Golgi in yeasts. For example, yeasts have provided direct evidence for Golgi cisternal maturation, a mechanism that is likely to be broadly conserved. Here, we highlight features of the yeast Golgi as well as challenges that lie ahead.

Abbreviations: ER, endoplasmic reticulum, tER, transitional ER, TGN, trans-Golgi network

Keywords: Yeast, Golgi, Secretory pathway, Cisternal maturation, Transitional ER

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PII: S0014-5793(09)00864-3

doi:10.1016/j.febslet.2009.10.072

FEBS Letters
Volume 583, Issue 23 , Pages 3746-3751, 3 December 2009