FEBS Letters
Volume 583, Issue 24 , Pages 3895-3899, 17 December 2009

Systems biology from a yeast omics perspective

Edited by Stefan Hohmann

Department of Genetics, 300 Pasteur Dr, Stanford University, Stanford, CA 94305, United States

Received 23 October 2009; received in revised form 5 November 2009; accepted 5 November 2009. published online 09 November 2009.

Abstract 

Systems biology represents a paradigm shift from the study of individual genes, proteins or other components to that of the analysis of entire pathways, cellular, developmental, or organismal processes. Large scale studies, primarily initiated in Saccharomyces cerevisiae, have allowed the identification and characterization of components on an unprecedented level. Large scale interaction, transcription factor binding and phosphorylation data have enabled the elucidation of global regulatory networks. These studies have helped provide an understanding of cellular pathways and processes at a global and systems level.

Keywords: Systems biology, Genomics, Proteomics, Transcriptome, Phosphorylome, Saccharomyces cerevisiae

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PII: S0014-5793(09)00904-1

doi:10.1016/j.febslet.2009.11.011

FEBS Letters
Volume 583, Issue 24 , Pages 3895-3899, 17 December 2009

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