FEBS Letters
Volume 584, Issue 13 , Pages 2748-2758, 2 July 2010

Post-translational modifications in host cells during bacterial infection

Edited by Jan Rydström

  • David Ribet
  • ,
  • Pascale Cossart

      Affiliations

    • Corresponding Author InformationCorresponding author at: Unité des Interactions Bactéries-Cellules, Institut Pasteur, 25 rue du Dr Roux, 75015 Paris, France. Fax: +33 1 45 68 87 06.

Institut Pasteur, Unité des Interactions Bactéries-Cellules, Département de Biologie Cellulaire et Infection, F-75015 Paris, France

INSERM, U604, F-75015 Paris, France

INRA, USC2020, F-75015 Paris, France

Received 6 May 2010; accepted 10 May 2010. published online 19 May 2010.

Abstract 

Post-translational modification of proteins is a widespread mechanism used by both prokaryotic and eukaryotic cells to modify the activity of key factors that plays fundamental roles in cellular physiology. This review focuses on how bacterial pathogens can interfere with host post-translational modifications to promote their own survival and replication.

Keywords: Rho GTPase, Cytoskeleton, Ubiquitin, MAPK, SUMO, Pathogenesis, Listeria

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PII: S0014-5793(10)00405-9

doi:10.1016/j.febslet.2010.05.012

FEBS Letters
Volume 584, Issue 13 , Pages 2748-2758, 2 July 2010