FEBS Letters
Volume 584, Issue 17 , Pages 3752-3759, 10 September 2010

Comparative biology of telomeres: Where plants stand

Edited by Wilhelm Just

Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, Dr. Bohr-Gasse 3, 1030 Vienna, Austria

Received 12 May 2010; received in revised form 11 June 2010; accepted 14 June 2010. published online 18 June 2010.

Abstract 

Telomeres are essential structures at the ends of eukaryotic chromosomes. Work on their structure and function began almost 70 years ago in plants and flies, continued through the Nobel Prize winning work on yeast and ciliates, and goes on today in many model and non-model organisms. The basic molecular mechanisms of telomeres are highly conserved throughout evolution, and our current understanding of how telomeres function is a conglomeration of insights gained from many different species. This review will compare the current knowledge of telomeres in plants with other organisms, with special focus on the functional length of telomeric DNA, the search for TRF homologs, the family of POT1 proteins, and the recent discovery of members of the CST complex.

Keywords: Telomere, Telomerase, Arabidopsis, Genome stability, Plant

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PII: S0014-5793(10)00507-7

doi:10.1016/j.febslet.2010.06.017

FEBS Letters
Volume 584, Issue 17 , Pages 3752-3759, 10 September 2010