Comparative biology of telomeres: Where plants stand
Abstract
Telomeres are essential structures at the ends of eukaryotic chromosomes. Work on their structure and function began almost 70 years ago in plants and flies, continued through the Nobel Prize winning work on yeast and ciliates, and goes on today in many model and non-model organisms. The basic molecular mechanisms of telomeres are highly conserved throughout evolution, and our current understanding of how telomeres function is a conglomeration of insights gained from many different species. This review will compare the current knowledge of telomeres in plants with other organisms, with special focus on the functional length of telomeric DNA, the search for TRF homologs, the family of POT1 proteins, and the recent discovery of members of the CST complex.
Keywords: Telomere, Telomerase, Arabidopsis, Genome stability, Plant
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PII: S0014-5793(10)00507-7
doi:10.1016/j.febslet.2010.06.017
© 2010 Federation of European Biochemical Societies
